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A Study At Vanderbilt on human consumption of HMB.

What were the results? In the first study, HMB greatly decreased the muscle proteolysis as well as the levels of plasma creatine phosphokinase. Additionally, the amount of weights lifted increased with HMB supplementation when compared with the unsupplemented group. During each week of the second study, fat-free mass was significantly increased in HMB supplemented subjects compared with the unsupplemented group. Nissen and colleagues thus concluded that supplementation with either 1.5 or 3 g HMB/day can partly prevent exercise-induced proteolysis and/or muscle damage. Additionally, the dietary supplementation of HMB can result in larger gains in muscle-mass associated with resistance training.